Insulin signaling
Metabolism
Metabolic disease
Throughout the day, during and between meals, the body must continuously determine:
(1) how much glucose, fat, and cholesterol should be generated or eliminated, and (2) how to transport those molecules between tissues and fluids. Our lab investigates how insulin signaling controls these processes, and how they become disrupted in conditions like insulin resistance, diabetes, liver disease, and atherosclerosis.
#metabolism #cholesterol #bile-acids #lipids #glucose #insulin #diabetes #obesity #atherosclerosis #liver #gut
Publications
2021-2023
2019
2018
microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function
Langlet F, Tarbier M, Haeusler RA, Camastra S, Ferrannini E, Friedlander MR, and Accili D (2018)
Molecular Metabolism 17: 49-60
2016-2017
2014-2015
2012-2013
2010-2011